KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PVRL2
All Species:
9.7
Human Site:
S491
Identified Species:
30.48
UniProt:
Q92692
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92692
NP_001036189.1
538
57742
S491
P
P
A
V
E
D
V
S
L
D
L
E
D
E
E
Chimpanzee
Pan troglodytes
XP_512741
538
57838
S491
P
P
A
V
E
D
V
S
L
D
L
E
D
E
E
Rhesus Macaque
Macaca mulatta
NP_001037058
479
51804
P433
V
V
P
G
P
M
E
P
D
G
E
D
E
E
E
Dog
Lupus familis
XP_852651
541
57957
G494
P
G
P
P
A
M
E
G
V
S
L
D
L
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P32507
530
57299
S482
P
N
V
V
E
G
V
S
L
S
L
E
D
E
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519017
849
91247
S568
E
A
G
T
K
N
G
S
L
L
L
R
D
V
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087644
463
50753
V416
E
E
R
M
K
Y
D
V
L
E
D
D
D
E
E
Zebra Danio
Brachydanio rerio
Q58EG3
574
63977
R526
S
P
A
H
H
I
Q
R
S
S
L
Q
P
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
69.3
79.1
N.A.
74.7
N.A.
N.A.
33
N.A.
32.5
25.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
74.3
85.7
N.A.
82.9
N.A.
N.A.
43.1
N.A.
45.9
41.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
20
N.A.
73.3
N.A.
N.A.
26.6
N.A.
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
40
N.A.
73.3
N.A.
N.A.
40
N.A.
53.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
38
0
13
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
25
13
0
13
25
13
38
63
0
13
% D
% Glu:
25
13
0
0
38
0
25
0
0
13
13
38
13
75
63
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
13
13
0
13
13
13
0
13
0
0
0
0
0
% G
% His:
0
0
0
13
13
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
63
13
75
0
13
0
0
% L
% Met:
0
0
0
13
0
25
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
13
0
0
0
0
0
0
0
0
0
% N
% Pro:
50
38
25
13
13
0
0
13
0
0
0
0
13
0
13
% P
% Gln:
0
0
0
0
0
0
13
0
0
0
0
13
0
13
0
% Q
% Arg:
0
0
13
0
0
0
0
13
0
0
0
13
0
0
0
% R
% Ser:
13
0
0
0
0
0
0
50
13
38
0
0
0
0
13
% S
% Thr:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
13
13
13
38
0
0
38
13
13
0
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _